BC 060 – Thérapie antiplaquettaire double jusqu’à 72 heures après un événement vasculaire cérébral ischémique (étude INSPIRES)

Épisode de BaladoCritique - club de lecture médical par Dr Luc Lanthier et collaborateurs · 22 janvier 2024 · 42 min

Dans cette 60e baladodiffusion, le Dr Luc Lanthier discute de l’efficacité d’une thérapie antiplaquettaire double pour 21 jours débutée jusqu’à 72 heures à la suite d’un événement vasculaire cérébral ischémique, en plus de réviser la littérature médicale de décembre 2023.

Quiz clinique (2 min 12), présentation principale (2 min 43), critique (26 min 05), autres articles (33 min 14), réponse au quiz clinique (36 min 46)

Référence principale :

Gao Y, Chen W, Pan Y, Jing J, Wang C, Johnston SC, et al. Dual Antiplatelet Treatment up to 72 Hours after Ischemic Stroke. N Engl J Med. 2023;389(26):2413-24. PubMed PMID: 38157499.

Articles associés :

Kim AS. Extending Dual Antiplatelet Therapy for TIA or Stroke. N Engl J Med. 2023;389(26):2478-9. PubMed PMID: 38157504.

Kleindorfer DO, Towfighi A, Chaturvedi S, Cockroft KM, Gutierrez J, Lombardi-Hill D, et al. 2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack: A Guideline From the American Heart Association/American Stroke Association. Stroke. 2021;52(7):e364-e467. PubMed PMID: 34024117.

Wein T, Lindsay MP, Gladstone DJ, Poppe A, Bell A, Casaubon LK, et al. Canadian Stroke Best Practice Recommendations, seventh edition: acetylsalicylic acid for prevention of vascular events. CMAJ. 2020;192(12):E302-E11. PubMed PMID: 32392513.

Johnston SC, Amarenco P, Denison H, Evans SR, Himmelmann A, James S, et al. Ticagrelor and Aspirin or Aspirin Alone in Acute Ischemic Stroke or TIA. N Engl J Med. 2020;383(3):207-17. PubMed PMID: 32668111.

Johnston SC, Elm JJ, Easton JD, Farrant M, Barsan WG, Kim AS, et al. Time Course for Benefit and Risk of Clopidogrel and Aspirin After Acute Transient Ischemic Attack and Minor Ischemic Stroke. Circulation. 2019;140(8):658-64. PubMed PMID: 31238700.

Johnston SC, Easton JD, Farrant M, Barsan W, Conwit RA, Elm JJ, et al. Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA. N Engl J Med. 2018;379(3):215-25. PubMed PMID: 29766750.

Wang Y, Wang Y, Zhao X, Liu L, Wang D, Wang C, et al. Clopidogrel with aspirin in acute minor stroke or transient ischemic attack. N Engl J Med. 2013;369(1):11-9. PubMed PMID: 23803136.

Diener HC, Bogousslavsky J, Brass LM, Cimminiello C, Csiba L, Kaste M, et al. Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): randomised, double-blind, placebo-controlled trial. Lancet. 2004;364(9431):331-7. PubMed PMID: 15276392.

Autres articles d’intérêt récent :

Carson JL, Brooks MM, Hebert PC, Goodman SG, Bertolet M, Glynn SA, et al. Restrictive or Liberal Transfusion Strategy in Myocardial Infarction and Anemia. N Engl J Med. 2023;389(26):2446-56. PubMed PMID: 37952133.

Rajkumar CA, Foley MJ, Ahmed-Jushuf F, Nowbar AN, Simader FA, Davies JR, et al. A Placebo-Controlled Trial of Percutaneous Coronary Intervention for Stable Angina. N Engl J Med. 2023;389(25):2319-30. PubMed PMID: 38015442.

Mensah GA, Fuster V, Murray CJL, Roth GA, Global Burden of Cardiovascular D, Risks C. Global Burden of Cardiovascular Diseases and Risks, 1990-2022. J Am Coll Cardiol. 2023;82(25):2350-473. PubMed PMID: 38092509.

Freund Y, Viglino D, Cachanado M, Cassard C, Montassier E, Douay B, et al. Effect of Noninvasive Airway Management of Comatose Patients With Acute Poisoning: A Randomized Clinical Trial. JAMA. 2023;330(23):2267-74. PubMed PMID: 38019968.

Wilson E, Goswami J, Baqui AH, Doreski PA, Perez-Marc G, Zaman K, et al. Efficacy and Safety of an mRNA-Based RSV PreF Vaccine in Older Adults. N Engl J Med. 2023;389(24):2233-44. PubMed PMID: 38091530.

Dodick DW, Goadsby PJ, Schwedt TJ, Lipton RB, Liu C, Lu K, et al. Ubrogepant for the treatment of migraine attacks during the prodrome: a phase 3, multicentre, randomised, double-blind, placebo-controlled, crossover trial in the USA. Lancet. 2023;402(10419):2307-16. PubMed PMID: 37979595.

Khan SS, Coresh J, Pencina MJ, Ndumele CE, Rangaswami J, Chow SL, et al; American Heart Association. Novel Prediction Equations for Absolute Risk Assessment of Total Cardiovascular Disease Incorporating Cardiovascular-Kidney-Metabolic Health: A Scientific Statement From the American Heart Association. Circulation. 2023;148(24):1982-2004. PubMed PMID: 37947094.

Guides de pratique :

Humphrey MB, Russell L, Danila MI, Fink HA, Guyatt G, Cannon M, et al. 2022 American College of Rheumatology Guideline for the Prevention and Treatment of Glucocorticoid-Induced Osteoporosis. Arthritis Rheumatol. 2023;75(12):2088-102. PubMed PMID: 37845798.

Singal AG, Llovet JM, Yarchoan M, Mehta N, Heimbach JK, Dawson LA, et al. AASLD Practice Guidance on prevention, diagnosis, and treatment of hepatocellular carcinoma. Hepatology. 2023;78(6):1922-65. PubMed PMID: 37199193.

Références du quiz clinique :

Trubiano JA, Vogrin S, Chua KYL, Bourke J, Yun J, Douglas A, Stone CA, Yu R, Groenendijk L, Holmes NE, Phillips EJ. Development and Validation of a Penicillin Allergy Clinical Decision Rule. JAMA Intern Med. 2020;180(5):745-752. PubMed PMID: 32176248.

Copaescu AM, Vogrin S, James F, Chua KYL, Rose MT, De Luca J, et al. Efficacy of a Clinical Decision Rule to Enable Direct Oral Challenge in Patients With Low-Risk Penicillin Allergy: The PALACE Randomized Clinical Trial. JAMA Intern Med. 2023;183(9):944-952. PubMed PMID: 37459086.

Su C, Belmont A, Liao J, Kuster JK, Trubiano JA, Kwah JH. Evaluating the PEN-FAST Clinical Decision-making Tool to Enhance Penicillin Allergy Delabeling. JAMA Intern Med. 2023;183(8):883-885. PubMed PMID: 37338869.

Wijnakker R, van Maaren MS, Bode LGM, Bulatovic M, Hendriks BJC, Loogman MCM, et al. The Dutch Working Party on Antibiotic Policy (SWAB) guideline for the approach to suspected antibiotic allergy. Clin Microbiol Infect. 2023;29(7):863-875. PubMed PMID: 37068548.

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